The long-acting form of oxycodone may cause less constipation than the immediate-acting form. Severe but less common side effects can occur with Vicodin and Percocet medications.
If you have any of these side effects, call or go to the nearest emergency room right away. These side effects may include:. Both Vicodin and Percocet affect your mental and physical abilities, such as judgment and reflexes.
Vicodin and Percocet are powerful drugs, so you should be aware of the risks involved with taking them. Even if you take them exactly as prescribed, Vicodin or Percocet may become habit-forming.
In other words, these drugs can cause physical or mental dependence. For this reason, doctors are cautious when prescribing them. There is also the risk of a withdrawal response when stopping these drugs. If you take either drug for more than a few days, talk to your doctor before you stop.
Your doctor can help you taper off the medication slowly. This reduces your risk of withdrawal. Be sure to take these drugs exactly as your doctor prescribes to reduce your risk of both dependence and withdrawal problems. Like most drugs, Vicodin and Percocet can interact with other medications. This means that when used with certain other drugs, these medications can cause effects that can be dangerous.
Before you take Vicodin or Percocet, tell your doctor about all other medications you take, including vitamins and supplements. Vicodin and Percocet interact with many of the same drugs. For more information, visit the interaction sections for Vicodin and Percocet.
If you have certain health conditions, taking Vicodin or Percocet could increase certain risks. Before taking Vicodin or Percocet, be sure to tell your doctor if you have constipation or intestinal blockage. Opioid analgesics can cause increased constipation, so ask your doctor if you should avoid taking them.
You should not drink alcohol while taking either Vicodin or Percocet. Combining alcohol and these painkillers can cause extreme dizziness or drowsiness, and can even be deadly. In some cases, taking one of these drugs with alcohol can cause liver damage. This is true if you drink more than three alcoholic drinks per day, have alcoholic liver disease, or have a history of alcohol abuse. Vicodin and Percocet are opioid pain medications that are similar in many ways.
Some of the main ways in which they differ are strengths and cost. If your doctor feels you need Vicodin or Percocet for your pain, they will choose the drug for you based on several factors. These factors include your health history and how your body has reacted to pain medications in the past. If you have questions about your prescription or about either of these drugs, be sure to ask your doctor.
Questions to ask your doctor might include:. Methods: This prospective, double-blind, randomized, controlled trial was conducted at an urban trauma center with an annual census of 65, Eligible participants included ED patients over the age of 12 years with fractures who consented to participate.
Subjects were randomized to receive either oxycodone 5 mg orally [po] with acetaminophen, or hydrocodone 5 mg po with acetaminophen. Measurements included demographic information; pain scores on a verbal numeric rating scale at baseline and at 30 and 60 minutes; vital signs at baseline and at 30 and 60 minutes; and adverse effects.
Results: Seventy-three subjects were randomized to receive oxycodone or hydrocodone. Taking Percocet or Vicodin with medications that increase serotonin levels increases the risk of serotonin syndrome, a very serious or even life-threatening condition.
These drugs include certain antidepressants, muscle relaxants, MAO inhibitors MAO inhibitors should not be used within 14 days of Percocet or Vicodin , and triptans. Other drug interactions may occur. Consult your healthcare provider for a full list of drug interactions of Percocet and Vicodin. Both Percocet and Vicodin come with a boxed black box warning , which is the strongest warning required by the FDA.
Here are other warnings:. Percocet is an opioid pain reliever and contains oxycodone and acetaminophen. It should only be used for severe, acute pain, for a short period of time, unless otherwise instructed by your healthcare provider. Vicodin is also an opioid pain reliever. It contains hydrocodone and acetaminophen. It is used for severe, acute pain, and should only be used for a short period of time unless otherwise instructed by your healthcare provider.
They are similar, but not the same. Both contain Tylenol or acetaminophen. Percocet also contains oxycodone, a strong painkiller. Vicodin also contains hydrocodone, which is a strong painkiller. Both drugs seem to be similarly effective, as seen in the studies described above. If you have severe, acute pain, that is not controlled with a non-opioid medication, your doctor may recommend trying Percocet or Vicodin on a short-term basis.
Consult your healthcare provider for more information. Taking Percocet or Vicodin can cause harm to the baby, and taking it for a prolonged period of time can cause neonatal opioid withdrawal syndrome also known as neonatal abstinence syndrome , which can be life-threatening.
No , you should not use Percocet or Vicodin with alcohol. The combination could increase the risk of CNS and respiratory depression, which could lead to a coma or death. Also, the combination of alcohol and acetaminophen can increase the risk for liver problems. Generally, no.
If you are taking an opioid for acute pain, you would not take another opioid. For example, patients should not take oxycodone with Vicodin because the combination increases the risk of CNS and respiratory depression, psychomotor impairment, low blood pressure, and severe constipation.
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